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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1704 All Species: 25.15
Human Site: S122 Identified Species: 46.11
UniProt: Q8IXQ4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IXQ4 NP_061029.2 340 38142 S122 L P P G F I K S T Q K S D K G
Chimpanzee Pan troglodytes XP_509661 340 38139 S122 L P P G F I K S T Q K S D K G
Rhesus Macaque Macaca mulatta XP_001094145 344 38614 S126 L P P G F I K S T Q K S D K G
Dog Lupus familis XP_851499 342 38712 S124 L P P G F I K S T Q K S D K G
Cat Felis silvestris
Mouse Mus musculus Q69ZC8 346 38936 S121 L P P G F I K S P Q K N D K G
Rat Rattus norvegicus Q4V893 348 39156 S123 L P P G F I K S P Q K N D K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514535 347 38704 N128 S S R E K E E N A S Y I S P S
Chicken Gallus gallus NP_001006270 350 39239 S124 L P P G F R K S A Q D T E S N
Frog Xenopus laevis NP_001089474 337 37926 Q119 P G F R R D S Q D E E G S D C
Zebra Danio Brachydanio rerio NP_001003473 405 45367 L173 L P P G F K R L D D N E E E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_996214 349 39457 P118 Q P Q A M I G P V L P S N L T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93591 297 33204 P94 F P S Q S Y G P S I P S N F R
Sea Urchin Strong. purpuratus XP_796639 403 45460 G174 Y G P S L P P G L H S N R M L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.3 91.5 N.A. 89.5 87.3 N.A. 64.2 68.8 63.2 47.1 N.A. 26.9 N.A. 27.6 37.9
Protein Similarity: 100 100 98.5 96.1 N.A. 93.6 93.3 N.A. 75.2 80 75.8 60.2 N.A. 41.5 N.A. 44.7 53.8
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. 0 53.3 0 33.3 N.A. 20 N.A. 13.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 13.3 66.6 13.3 53.3 N.A. 26.6 N.A. 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 16 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 8 0 0 16 8 8 0 47 8 0 % D
% Glu: 0 0 0 8 0 8 8 0 0 8 8 8 16 8 8 % E
% Phe: 8 0 8 0 62 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 16 0 62 0 0 16 8 0 0 0 8 0 0 47 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 54 0 0 0 8 0 8 0 0 0 % I
% Lys: 0 0 0 0 8 8 54 0 0 0 47 0 0 47 0 % K
% Leu: 62 0 0 0 8 0 0 8 8 8 0 0 0 8 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 8 24 16 0 8 % N
% Pro: 8 77 70 0 0 8 8 16 16 0 16 0 0 8 0 % P
% Gln: 8 0 8 8 0 0 0 8 0 54 0 0 0 0 0 % Q
% Arg: 0 0 8 8 8 8 8 0 0 0 0 0 8 0 8 % R
% Ser: 8 8 8 8 8 0 8 54 8 8 8 47 16 8 8 % S
% Thr: 0 0 0 0 0 0 0 0 31 0 0 8 0 0 8 % T
% Val: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _